Clinical research: Analysis populations and missing data

Introduction

What this guide covers

Introduction Chart from the original guide

Overview

Topics covered

• Introduction
• Analysis Populations and Missing Data
• The Estimates Framework (ICH E9(R1))
• Analysis Populations in Clinical Trials
• 1. Intention-to-Treat (ITT) Population
• 2. Modified Intent to Treat Population (Modified ITT, mITT)

Related concepts

Main connections

• Missing data & multiple imputation
• Variance & standard deviation
• Clinical trials & RCT design
• Mean & expected value
• Maximum likelihood estimation
• Permutation & exact tests

Compatible notation

Mathematical sample in LaTeX

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