Advanced & Applied Topics · Computational Biostatistics & Genomics

Computational Biostatistics: Machine Learning Methods

Public introduction · full guide in Eikos

Introduction

What this guide covers

Introduction Machine Learning · Advanced Statistical Methods

Overview

Topics covered

  • Introduction
  • Classical biostatistics versus Machine Learning
  • 1.1 The Curse of Dimensionality
  • 1.2 Bias-Variance Compromise in the Clinical Environment
  • Regularization Methods: Ridge, Lasso and Elastic Net
  • 2.1 Ridge Regression ( Regularization)

Related concepts

Main connections

  • Survival analysis & Kaplan-Meier
  • Regularization (Lasso / Ridge / Elastic Net)
  • Supervised machine learning
  • Overfitting & cross-validation
  • Unsupervised learning & clustering
  • Variance & standard deviation

Compatible notation

Mathematical sample in LaTeX

The expression is rendered accessibly, with its LaTeX source preserved below.

E[(y−f^(x))2]=Bias[f^(x)]2+Var[f^(x)]+σ2
View LaTeX sourceE\left[(y - \hat{f}(x))^2\right] = \text{Bias}\left[\hat{f}(x)\right]^2 + \text{Var}\left[\hat{f}(x)\right] + \sigma^2