Clinical Research: Introduction and Development of Drugs · Introduction

Introduction

What this guide covers

A comprehensive, graduate-level treatise on the biostatistical methodology, pharmacokinetic foundations, and clinical trial designs that govern contemporary scientific discovery.

Overview

Topics covered

Introduction
The Global Drug Development Process and its Design Philosophy
Phase I Clinical Trials: Tolerability, Pharmacokinetics and Pharmacodynamics
Fundamentals of Pharmacokinetic Modeling (PK)
Dose Escalation Design and Bayesian Inference
Phase II Clinical Trials: Proof of Concept and Multistage Designs

Related concepts

Main connections

Compatible notation

Mathematical sample in LaTeX

The expression is rendered accessibly, with its LaTeX source preserved below.

\text{HED (human equivalent dose)} = \text{NOAEL}_{\text{animal}} \times \left( \frac{\text{Peso}_{\text{animal}}}{\text{Peso}_{\text{humano}}} \right)^{1 - b}

View LaTeX source

\text{HED (human equivalent dose)} = \text{NOAEL}_{\text{animal}} \times \left( \frac{\text{Peso}_{\text{animal}}}{\text{Peso}_{\text{humano}}} \right)^{1 - b}